Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Quantity
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766
Tocris Bioscience™ GSK'872
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective RIP3 kinase inhibitor
| CAS | 1346546-69-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-5-Benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H17N3O2S2 |
| Formula Weight | 383.49 |
767
Tocris Bioscience™ endo-IWR 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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endo-IWR 1 synthesized to Ancillary Material Grade
768
Tocris Bioscience™ L-Ascorbic acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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L-Ascorbic acid synthesized to Ancillary Material Grade
769
Tocris Bioscience™ NADA-green
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fluorescent Probes for Imaging Bacteria
770
Tocris Bioscience™ Surfen
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Heparin sulfate antagonist
| Target | Compounds for ESC/iPSC Proliferation and Renewal |
|---|---|
| CAS | 5424-37-3 |
| Purity | 98% |
| Chemical Name or Material | N,N'-Bis(4-amino-2-methyl-6-quinolinyl)urea dihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H20N6O0.2 HCl |
| Formula Weight | 445.35 |
771
Tocris Bioscience™ Dasatinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Highly potent pan-Src/Bcr-Abl inhibitor
772
Tocris Bioscience™ dTAG-7
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
773
Tocris Bioscience™ Cyclosporin H
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Enhances lentiviral transduction
774
Tocris Bioscience™ dTAG-13
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
775
Tocris Bioscience™ LY 450139
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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γ-secretase pseudo-inhibitor
| CAS | 425386-60-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H27N3O4 |
| Formula Weight | 361.44 |
776
Tocris Bioscience™ TAK 242
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Toll-like receptor 4 (TLR4) signaling inhibitor
777
Tocris Bioscience™ BAY 826
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent Tie2 inhibitor
| CAS | 1448316-08-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H19F5N6OS |
| Formula Weight | 558.53 |
778
Tocris Bioscience™ SGC GAK 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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High affinity cyclin G associated kinase (GAK) inhibitor
| CAS | 2226517-76-4 |
|---|---|
| Purity | 99% |
| Chemical Name or Material | 6-Bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H17BrN2O3 |
779
Tocris Bioscience™ NGI 1
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral
| Target | Other Transferase Inhibitors |
|---|---|
| CAS | 790702-57-7 |
| Purity | 98% |
| Chemical Name or Material | 5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C17H22N4O3S2 |
| Formula Weight | 394.51 |
780
Tocris Bioscience™ HADA
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fluorescent Probes for Imaging Bacteria